SUMMARY OF T CELLS
- Cell mediated response
- T cells are lymphocytes
- Triggered by antigens
- Produced in the Bone Marrow, matures in the thymus
- Determines between self and non-self cells via MHC class markers (antigens).
- When cell is seen as non-self, triggers a response to eliminate foreign matter from the body.
- Antigen-presenting cells can also be recognised as non-self cells by T cells, also triggering response.
- T Cell receptors allow T cells to recognise antigens.
- T CELLS DO NOT MAKE ANTIBODIES
- When T cell come across foreign antigen and binds to receptor, they mass reproduce and from memory T cells.
- Memory T cells last up to 15-20 years
- T helper cells recognise antigens on MHC class 2 on antigen-presenting cells. Only responds to cancerous cells, transplant tissue and infecting cells. Also stimulates B cells, which help kill antigen.
- T cytotoxic cells respond to cancerous cells and infected cells, tries to kill of by releasing protein chemicals that make holes the cell membrane of infected cells.
- T suppressor cells suppress the initial response to an antigen once the antigen has been killed.
- T cells work with B cells to kill of any antigens.